Journal article
Lipidated polymers for the stabilization of cubosomes: Nanostructured drug delivery vehicles
JL Grace, N Alcaraz, NP Truong, TP Davis, BJ Boyd, JF Quinn, MR Whittaker
Chemical Communications | Published : 2017
DOI: 10.1039/c7cc05842j
Abstract
Lipidated polymers, like their protein counterparts, may be useful in fields as diverse as biochemistry and drug delivery. As such, strategies for preparing lipidated polymers with defined molecular architecture are clearly warranted. Herein, we describe a broadly-applicable methodology for synthesizing such lipidated materials, and demonstrate how they can be applied to the preparation of nanostructured drug delivery vehicles.
Grants
Awarded by Australian Research Council
Funding Acknowledgements
We acknowledge the Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology (CE140100036). JLG, JFQ and TPD acknowledge the award of a RTP stipend, ARC Future Fellowship and Australian Laureate Fellowship respectively. We thank Julian Ratcliffe and Lynne Waddington from the Cryo-TEM facility at CSIRO manufacturing, and the SAXS/WAXS beamline at the Australian Synchrotron.